Juvederm Ultra Plus
Everything you need to know about Juvederm Ultra Plus
Juvederm Ultra Plus was one of the first Juvederm hyaluronic acid dermal fillers available for facial rejuvenation. It was specifically created to treat deep wrinkles and folds and restore volume in areas such as the nasolabial lines, smile lines, oral commissures, and lips. Volume loss is a common sign of aging that occurs as the skin’s collagen and hyaluronic acid levels decrease. When expertly injected by a board-certified dermatologist, Juvederm Ultra Plus can restore lost volume and provide a natural-looking, long-lasting, more youthful appearance. Dr. Michele Green was one of NYC’s first dermatologists to use Juvederm Ultra Plus for facial rejuvenation and is a leading expert in cosmetic dermatology and dermal filler procedures.
Juvederm Ultra Plus is part of the Juvederm line of fillers by Allergan, the company that also produces Botox. The FDA approved it for the treatment of moderate to severe facial wrinkles, including nasolabial folds, marionette lines, and oral commissures. This dermal filler is composed of a densely cross-linked hyaluronic acid gel, making it thicker and longer-lasting. Its structure supports areas with significant volume loss and maintains its shape over time. The hyaluronic acid also attracts moisture, improving hydration and creating a smoother skin texture. Juvederm Ultra Plus can also be selected for lip augmentation to restore age-related volume loss or to achieve fuller, more symmetrical lips. With her deep understanding of facial anatomy and filler technology, Dr. Green uses Juvederm Ultra Plus to produce smooth, sculpted results that enhance overall appearance while preserving facial harmony.
Dr. Michele Green is a board-certified dermatologist and an Allergan Platinum Injector, consistently recognized for her exceptional artistry and meticulous attention to detail. She was among the first in New York City to introduce Juvederm Ultra Plus to her private dermatology practice, bringing experience and precision to every procedure. Dr. Green has been named a top dermatologist in New York by Castle Connolly, Super Doctors, New York Magazine, and The New York Times for her expertise and dedication to her patients. Located in the heart of Manhattan’s Upper East Side, her private dermatology office offers a discreet, welcoming environment where patients receive world-class aesthetic care. During your consultation, Dr. Green will work with you to develop a personalized plan that aligns with your goals and highlights your best features.
What is Juvederm Ultra Plus?
Juvederm Ultra Plus is a hyaluronic acid dermal filler developed by Allergan Aesthetics and was among the first Juvederm fillers FDA-approved in 2006. It was specifically formulated as a thicker gel to add volume and smooth moderate-to-severe facial wrinkles and folds around the mouth, improving the appearance of nasolabial folds and marionette lines. It can also be used to enhance the lips by adding volume for a more dramatic pout. The treatment provides long-lasting results, with effects lasting up to 9 months after injections.

Juvederm – 2 weeks before and after
How does Juvederm Ultra Plus work?
Juvederm Ultra Plus is composed of hyaluronic acid, a naturally occurring sugar that attracts moisture to improve skin elasticity and hydration. As we age, our skin loses collagen, resulting in facial sagging, volume loss, and decreased elasticity. With hyaluronic acid, Juvederm products help combat signs of aging by smoothing wrinkles, lifting the mid-face, and filling deep folds and wrinkles to achieve a more youthful look. A key feature of Juvederm Ultra Plus is its inclusion of lidocaine, a local anesthetic that greatly enhances patient comfort during injections, making the procedure more pleasant. The treatment is non-invasive and requires no recovery time, unlike a surgical facelift, which has a longer healing process. Many patients opt for Juvederm Ultra Plus for quick, simple treatments to improve facial wrinkles.
What areas can Juvederm Ultra Plus treat?
Juvederm Ultra Plus is designed to smooth moderate to severe creases and folds in the lower face and to enhance the shape, definition, and volume of the lips. Juvederm Ultra Plus can treat:
- Nasolabial folds (also known as smile lines)
- Oral commissures
- Corners of the mouth
- Marionette lines
- Lips
- Jowls
Who is a good candidate for Juvederm Ultra Plus?
Ideal candidates for Juvederm Ultra Plus are individuals over 21 in good overall health who want to treat moderate to severe facial wrinkles, enhance lip volume, or correct facial asymmetry. Patients should not be pregnant, breastfeeding, or have a history of severe allergic reactions or allergies to lidocaine or gram-positive bacteria used to produce hyaluronic acid fillers. Any bleeding disorders or medications that affect clotting should be discussed with Dr. Green before treatment. During your consultation, Dr. Green will carefully review your medical history to determine if you are a suitable candidate.
What can I expect during my Juvederm treatment?
The treatment process for Juvederm Ultra Plus is straightforward and painless. First, you’ll meet with Dr. Green for a consultation to discuss your medical history, skin concerns, and goals. Medical photographs will be taken of the area to monitor your progress. Then, Dr. Green will collaborate with you to create a treatment plan tailored to your needs. After confirming that Juvederm Ultra Plus is appropriate for you, she will go over pre- and post-procedure instructions. The procedure can be performed on the same day as the consultation or scheduled for a later date, based on your availability and preference.
On the day of your procedure, a topical numbing cream will be applied one hour prior to your cosmetic injections to reduce discomfort. When you arrive at Dr. Green’s private NYC dermatology office, the treatment area will be thoroughly cleaned and sterilized. Dr. Green then uses a fine needle to inject the filler into the targeted area. An ice pack will be applied immediately afterward to help minimize bruising or swelling. There is no downtime required so that you can resume your normal activities right after treatment. You will start to see results immediately, though full results may take up to two weeks to appear fully.
What are the side effects of Juvederm Ultra Plus?
The most common side effects of Juvederm Ultra Plus are mild bruising, swelling, and redness at or near the injection site. These symptoms are typical of other facial injections and will disappear on their own shortly after treatment. To reduce the risk of bruising, Dr. Green advises avoiding blood thinners, NSAIDs, fish oil, and vitamin E for one week before and after the procedure. Patients prone to bruising can take Arnika Forte, an over-the-counter herbal supplement, to help lessen bruising.
However, more serious side effects can occur if an injector uses an incorrect technique. Injecting a dermal filler into a blood vessel can cause an occlusion, which requires immediate medical attention. Specifically, overfilling the lips can cause filler migration, leading to lumps and an uneven appearance. When getting dermal filler injections, it is essential to seek out an experienced, board-certified dermatologist such as Dr. Michele Green, who has extensive knowledge of facial anatomy. The risk of infection is also low when a board-certified dermatologist performs the procedure in a medical setting. Dr. Green has over 25 years of experience injecting patients with dermal fillers and will use her medical expertise to ensure your treatment is safe and effective.
What is the recovery time after Juvederm Ultra Plus?
Following aftercare instructions is essential to minimize the side effects of Juvederm injections. Dr. Green recommends that patients avoid intense exercise and refrain from using the sauna for the first 48 hours after treatment, as these activities can increase redness and swelling in the treated area. Additionally, it is wise to avoid blood thinners for one week because they can raise the risk of bruising at the injection site. Patients who experience bruising may consider taking Arnika Forte to help speed recovery.

How long does Juvederm Ultra Plus last?
Juvederm Ultra Plus can last for 9-12 months, depending on the patient’s natural metabolism and the depth of the wrinkles or folds. Since hyaluronic acid fillers break down over time, many patients choose yearly touch-up treatments to preserve their results. When you receive treatment with Dr. Green, she will create a personalized schedule tailored to your aesthetic needs and goals.
Is Juvederm Ultra Plus safe?
Absolutely! Juvederm Ultra Plus is an FDA-approved dermal filler, which means it has undergone thorough testing to verify its safety. It is composed of hyaluronic acid, a substance that helps hydrate and volumize the skin. Since hyaluronic acid naturally exists in the body, the risk of allergic reactions after treatment is very low. For years, patients have chosen Juvederm Ultra Plus for its ability to improve the look of deeper folds and wrinkles and to contour the lips, with no downtime or major side effects. To prioritize safety, it’s best to consult an experienced, board-certified dermatologist like Dr. Michele Green. Dr. Green is a platinum-level Allergan injector with more than 25 years of experience using dermal fillers for facial rejuvenation. When you get your Juvederm Ultra Plus injections from Dr. Green, she’ll use her medical expertise to administer the treatment safely and help you look and feel your best again.
Can Juvederm Ultra Plus be combined with Botox?
Yes! Botox is often combined with Juvederm Ultra Plus for comprehensive facial rejuvenation. Botox is a neuromodulator that treats dynamic wrinkles, which are lines that appear with facial movements. It is commonly used to treat horizontal forehead lines caused by raising the eyebrows, glabellar or “11” lines from frowning, and crow’s feet around the eyes resulting from smiling, squinting, or laughing. Botox is a neurotoxin that temporarily relaxes targeted muscles, reducing their contractions and creating smooth, wrinkle-free skin. As these treatments address different areas of the face, many patients receive both Botox and Juvederm Ultra Plus injections during the same visit to address age-related and dynamic fine lines, as well as volume loss around the mouth.
Can you use Juvederm Ultra Plus with other Juvederm fillers?
Absolutely! Besides Juvederm Ultra Plus, there are six other Juvederm fillers, each with a different formulation and purpose. Patients often combine various Juvederm fillers for complete facial rejuvenation. Dr. Green will evaluate your facial anatomy and skin concerns to create a personalized Juvederm treatment plan designed to help you look and feel your best.
- Juvederm Ultra XC, the original Juvederm filler, restores lost facial volume, smooths mild to moderate nasolabial folds, smile lines, and marionette lines. It also adds volume and symmetry to the lips while enhancing the appearance of “smoker’s lines.”
- Juvederm Voluma XC is mainly used to add volume and lift the cheeks. It is the only FDA-approved non-surgical option for restoring cheek and mid-face volume and achieving a younger, plumper look.
- Juvederm Vollure XC treats moderate to severe facial wrinkles and folds. Juvederm Vollure is thinner in consistency than Juvederm Ultra Plus, allowing it to smooth out wrinkles without adding excessive volume.
- Juvederm Volbella XC is a smooth gel filler ideal for subtle lip enhancement, as it can perfectly augment the lips and improve the appearance of lines in the perioral area. Juvederm Volbella can also be used to treat undereye hollows.
- Juvederm Volux XC improves the jawline and chin for a more contoured appearance. Juvederm Volux is the only FDA-approved hyaluronic acid filler used to address moderate to severe loss of jawline definition.
- Skinvive by Juvederm is an FDA-approved filler that enhances hydration and smoothness in the cheeks. SkinVive contains hyaluronic acid microdroplets that help the skin retain its natural moisture and softness and can stimulate collagen production to improve skin elasticity.

Frequently Asked Questions (FAQs) about Juvederm Ultra Plus:
Is Juvederm Ultra Plus FDA-approved?
Yes, Juvederm Ultra Plus was first FDA-approved in 2006 for correcting moderate to severe nasolabial and marionette lines, as well as for enhancing the shape and contour of the lips. Juvederm Ultra Plus received FDA approval alongside Juvederm Ultra, and these fillers are often referred to as the original Juvederm fillers.
How is Juvederm Ultra Plus different from Juvederm Voluma?
Juvederm Voluma is one of the thickest fillers in the Juvederm family. This hyaluronic acid filler is ideal for patients seeking to restore volume in the cheeks or improve chin definition. Juvederm Ultra Plus, a thinner filler, effectively smooths fine lines, wrinkles, and folds such as nasolabial lines and marionette lines. Combining Juvederm Ultra Plus and Juvederm Voluma in a treatment plan can address multiple areas of volume loss for comprehensive facial rejuvenation.
Is Juvederm Ultra Plus better than regular Juvederm?
Juvederm is a family of hyaluronic acid-based dermal fillers designed to restore volume, smooth wrinkles, and enhance facial features. Juvederm Ultra and Juvederm Ultra Plus are the original Juvederm dermal fillers, both approved by the FDA in 2006. These hyaluronic acid fillers are excellent options for restoring facial volume and reducing fine lines, wrinkles, and folds. The main difference lies in the gel consistency: Juvederm Ultra Plus is thicker and more stable than Juvederm Ultra. Its increased thickness provides more volume for deeper folds, facial wrinkles, and thin lips, and the results tend to last a bit longer. Despite these differences, both fillers are highly effective for facial rejuvenation. The choice of which Juvederm filler to include in your treatment plan will depend on your individual needs and aesthetic goals, which you will discuss in detail with Dr. Green during your initial consultation.
Can Juvederm Ultra Plus help with deep wrinkles?
Yes, Juvederm Ultra Plus can effectively treat deep wrinkles, especially in the nasolabial folds, marionette lines, and oral commissures. This dermal filler has a slightly thicker consistency than Juvederm Ultra, providing greater structural support and volume, making it ideal for smoothing deeper wrinkles and creases in the lower face. When you meet with Dr. Green at her private NYC dermatology office, she will assess your facial structure and deep wrinkles to determine if Juvederm Ultra Plus is the right choice for you.
Can Juvederm Ultra Plus improve nasolabial folds?
Yes! Juvederm is an extremely popular injectable gel used to improve the appearance of nasolabial folds. This hyaluronic acid filler can add volume to the area, smooth folds, and provide flexibility to ensure results that look natural. Additionally, its highly cross-linked hyaluronic acid formulation makes it more stable, allowing patients to enjoy long-lasting results.
Can Juvederm Ultra Plus be used for cheeks?
Juvederm Ultra Plus XC is an excellent hyaluronic acid dermal filler mainly used to treat fine lines and deep creases in the nasolabial folds and marionette lines. It is not typically used for the cheeks. Within the Juvederm product line, Juvederm Voluma is great for restoring midface volume and improving cheek contour. Its thicker consistency makes it suitable for use in the cheek area for most patients. During your consultation, Dr. Green will choose the right Juvederm filler for your facial rejuvenation plan based on your specific skin concerns and overall aesthetic goals.

Female patient treated with Juvederm Ultra Plus
Can Juvederm Ultra Plus be used for lips?
Yes! Juvederm Ultra Plus is a popular choice for patients seeking fuller, more defined lips. Its thicker formula creates a plumper, more voluminous look and is ideal for correcting asymmetry or restoring lost facial volume due to aging. Additionally, Juvederm Ultra Plus effectively softens vertical lip lines, also known as smoker lines, which can form along the edges of the mouth. Since Juvederm Ultra Plus is FDA-approved, it is a safe option for those wanting fuller, plumper lips.
Can Juvederm Ultra Plus treat under-eye hollows?
No, Juvederm is not suitable for treating under-eye hollows. Using a thicker filler, such as Juvederm Ultra Plus, beneath the eyes can create an unnatural look. For under-eye hollows, a very smooth, flexible hyaluronic acid filler is best. Juvederm Volbella is commonly used here because it blends seamlessly into the skin and enhances contour without heaviness. When placed at the right depth, Juvederm Volbella can soften under-eye hollows, reduce discoloration from shadowing, and produce a more rested appearance that remains natural. Not every patient is a good candidate for under-eye filler, and results depend on skin quality and facial structure. Patients with significant skin laxity, prominent under-eye bags, or excess fat in the area may not achieve the desired results with dermal fillers alone. A thorough evaluation is crucial to determine whether Juvederm is appropriate or if another treatment would be more effective.

How many syringes of Juvederm Ultra Plus treatments will I need?
The number of Juvederm Ultra Plus treatments required varies based on the patient’s facial structure, the extent of volume loss, and their aesthetic goals. Patients with moderate facial lines may need only one syringe, while those with more pronounced folds and creases may require two or more syringes. Juvederm Ultra Plus provides long-lasting results, typically lasting 9 to 12 months. During your consultation with Dr. Green, she will help determine the number of syringes needed to reach your desired outcome. She will also develop a dermal filler schedule, usually involving annual appointments, to help maintain your results.
Does Juvederm Ultra Plus cause swelling or bruising?
Like any injection, Juvederm Ultra Plus treatment can cause swelling or bruising. These side effects are mild and usually go away on their own after the procedure. To help reduce swelling, ice packs will be applied to the injection site immediately after the filler injection. Dr. Green also recommends that patients avoid strenuous exercise, hot tubs, saunas, or steam rooms for 48 hours following the injections to limit swelling. Patients should also stop taking any blood-thinning medications or supplements, including NSAIDs, fish oil, and vitamin E, for a week before and after the treatment to help prevent bruising. If patients are prone to bruising, they can take Arnica, an over-the-counter herbal supplement, several days before and after the procedure to help prevent bruising and speed up healing if it occurs.
What are the risks and complications of Juvederm Ultra Plus?
There are very few risks or complications associated with Juvederm Ultra Plus, especially when administered by a board-certified dermatologist like Dr. Michele Green. Juvederm Ultra Plus is FDA-approved for treating lines, creases, and folds of the lower face and for lip augmentation. Common side effects include mild redness, swelling, and bruising, which usually resolve on their own after treatment. However, more serious side effects can happen. If a dermal filler is injected into a blood vessel, it can cause occlusion, requiring immediate medical attention. Juvederm Ultra Plus must be injected only by a board-certified dermatologist, such as Dr. Michele Green in New York City, who has the knowledge and skill to perform dermal filler injections safely and effectively.
Is Juvederm Ultra Plus safe during pregnancy or breastfeeding?
No. Juvederm Ultra Plus should not be used during pregnancy or while breastfeeding. There have not been any studies confirming the safety of dermal filler use during pregnancy or breastfeeding.
Can Juvederm Ultra Plus be dissolved?
Yes! Juvederm Ultra Plus can be dissolved with hyaluronidase injections. Hyaluronidase is an enzyme that breaks down the primary component of Juvederm fillers: hyaluronic acid. It is commonly used to eliminate unwanted results, such as lumps, bumps, or migrated filler. The number of treatments needed to dissolve the filler depends on the type and amount of filler used. Since Juvederm Ultra Plus contains cross-linked hyaluronic acid molecules, more than one session of hyaluronidase may be required to dissolve the dermal filler. Hyaluronidase acts quickly, and patients typically start to see results within one week after the injections, although full results may take up to two weeks due to swelling. Dr. Green will schedule a follow-up appointment two weeks after the procedure to assess the results and determine if additional sessions are necessary.
How much does Juvederm Ultra Plus cost?
The cost of Juvederm Ultra Plus injections varies based on several factors, including location, the amount of product needed, and your injector’s expertise. Patients with moderate to severe volume loss will require more syringes than those with mild loss. A board-certified dermatologist or plastic surgeon usually charges more than a nurse injector at a medical spa or clinic. However, because the procedure demands skill and precision, it is highly recommended to have the treatment performed by an experienced dermatologist, such as Dr. Michele Green in NYC, to ensure safe, natural-looking results. During your consultation, Dr. Green will review your goals and develop a personalized treatment plan tailored to your needs. Once the number of syringes needed is determined, the cost will be discussed.

Are Juvederm Ultra Plus results natural-looking?
Absolutely! Juvederm Ultra Plus is an excellent, natural-looking hyaluronic acid filler for enhancing nasolabial and marionette lines and defining the lips. It contains a unique cross-linked form of hyaluronic acid that helps restore lost volume and smooth wrinkles in the lower face. The best way to ensure your Juvederm Ultra Plus results look natural is to consult with an experienced, board-certified dermatologist like Dr. Michele Green. Dr. Green uses a “less-is-more” approach with each patient, tailoring their dermal filler plan to match their individual facial features. When you see Dr. Green for your Juvederm Ultra Plus treatment, she will achieve youthful, natural-looking results that last.
How do I get started with Juvederm filler today?
As we age, the production of collagen and elastin declines, leading to volume loss, skin sagging, and deeper wrinkles and folds. The Juvederm line of dermal fillers can restore facial volume, improve contours, and diminish the appearance of fine lines and deep creases. Juvederm Ultra Plus is an ideal hyaluronic acid filler for smoothing deep nasolabial folds, marionette lines, and lower facial folds, as well as adding volume to the lips, helping you achieve a natural-looking, long-lasting, youthful appearance. It is highly durable, making it an excellent choice for facial rejuvenation. An experienced injector, such as board-certified dermatologist Dr. Green in NYC, will create a personalized Juvederm Ultra Plus treatment plan tailored to your needs, resulting in a natural-looking, long-lasting, more youthful look.
Dr. Michele Green is an internationally recognized leader in cosmetic dermatology with over 25 years of experience providing top non-invasive treatments, including dermal filler injections, to patients worldwide. She was among the first dermatologists to incorporate Juvederm fillers into her patients’ rejuvenation plans and is an expert in dermal fillers, Botox, and other cosmetic procedures. Known for her holistic approach and ‘less is more’ philosophy, Dr. Green is consistently ranked among the best physicians in New York by Castle Connolly, Super Doctors, The New York Times, and New York Magazine. Please call our NYC office at 212-535-3088 or contact us online today to create a customized facial rejuvenation treatment plan with Dr. Green and learn more about whether Juvederm Ultra Plus is suitable for you.
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