The Cosmelan Peel by Mesoestetic is a medical-grade, multi-phase depigmentation treatment designed to improve all types of hyperpigmentation on the skin. Hyperpigmentation is a broad term used in dermatology to describe areas of skin discoloration that are darker than one’s natural skin tone. It occurs due to an overproduction of melanin, which can develop from factors such as sun damage, old acne lesions, underlying medical conditions, hormonal changes, certain medications, and others. While some forms of hyperpigmentation can be treated with lasers, others, such as melasma or post-inflammatory hyperpigmentation, require gentle chemical peels to prevent the worsening of pigmentation. Additionally, individuals with darker skin tones may not be suitable candidates for many laser treatments. Fortunately, Dr. Green offers the Cosmelan peel in her New York City dermatology office to address hyperpigmentation and melasma in patients of all skin tones and types.

The Cosmelan Peel reduces excess melanin and regulates its production in the epidermal and dermal layers of the skin. The Cosmelan treatment process involves the in-office application of the Cosmelan 1 mask, performed by Dr. Green, followed by a home care phase featuring a regimen of specialized skincare products, including the Cosmelan 2 depigmenting cream. Unlike other hyperpigmentation treatments, the Cosmelan peel is safe for patients with melasma and suitable for all skin types and tones, including those with darker skin tones. With minimal potential side effects, little downtime, and consistently impressive cosmetic results, the Cosmelan peel is one of the most popular cosmetic procedures offered at Dr. Michele Green’s private dermatology practice in New York City for achieving a healthy, radiant, and even skin tone.

Dr. Michele Green is an internationally recognized, board-certified cosmetic dermatologist with over twenty-five years of experience providing some of the world‘s most discerning individuals with top non-invasive treatment options, including Cosmelan treatment for hyperpigmentation and melasma. Dr. Green adopts a holistic approach and embraces a less-is-more philosophy regarding skin rejuvenation, customizing each patient’s treatment plan to meet their specific needs and aesthetic goals. She is consistently recognized as one of New York’s top dermatologists by Castle Connolly, New York Magazine, The New York Times, and Super Doctors for her dedication to her patients and her expertise. She is one of the few dermatologists in New York City who offers the Cosmelan treatment to achieve a healthy, radiant, and even skin tone.

What is the Cosmelan peel treatment?

The Cosmelan peel is the leading depigmentation treatment worldwide, designed to remove hyperpigmentation and regulate melanin production to prevent its return. Melanin, which gives the skin its color, is produced in excess, leading to hyperpigmentation and melasma. The Cosmelan peel not only eliminates existing melanin from the skin but also inhibits the tyrosinase enzyme, essential for melanin production. The Cosmelan peel can effectively eliminate or reduce melasma, post-inflammatory hyperpigmentation from old acne lesions, skin discoloration due to excessive sun exposure, and other forms of hyperpigmentation.

The Cosmelan peel consists of two steps. In the first step, an expert, such as board-certified dermatologist Dr. Green, applies the Cosmelan mask. This mask must be worn for a specific duration determined by Dr. Green, depending on the patient’s severity of hyperpigmentation, skin tone, and skin type. Once the specified time has elapsed, the patient removes the Cosmelan mask at home using a gentle cleanser. The second step of the Cosmelan peel involves the patient following a home treatment protocol that includes specially formulated depigmenting and anti-aging skincare products, such as the Cosmelan 2 cream. The Cosmelan 2 cream is a depigmenting treatment containing a blend of active ingredients with proven effectiveness, including kojic acid, salicylic acid, vitamin C, retinol, and Mesoestetic’s proprietary melaphenone complex. Dr. Green will also recommend that patients use a specific moisturizer and sunscreen from Mesoestetic, which complements the Cosmelan 2 cream to help preserve and enhance the treatment’s results. After completing the Cosmelan treatment, Dr. Green will create a customized skincare protocol to help you maintain the cosmetic results from the treatment and achieve long-lasting, clear, radiant skin.

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Before and after – 3 parts, Cosmelan treatment

What does Cosmelan do?

The Cosmelan peel serves as both a corrective and regulatory treatment. The Cosmelan Peel reduces excess melanin and regulates melanin production to eliminate or diminish various types of hyperpigmentation, including melasma, post-inflammatory hyperpigmentation due to acne scarring or surgery, sun damage, and other forms of skin discoloration. Utilizing a proprietary blend of active ingredients, the Cosmelan peel can:

  • Accelerate skin renewal to eliminate the buildup of melanin from the epidermis and dermis.
  • Reduce melanin production and diminish dark spots on the skin.
  • Prevent the transfer of melanin from melanocytes to keratinocytes, thereby inhibiting the migration of pigment to the epidermal layers of the skin.
  • Inhibit the activity of the tyrosinase enzyme, which is responsible for the initial step in melanin production.
  • Reduce the synthesis and minimize the production of melanin within melanocytes.

What types of hyperpigmentation does the Cosmelan peel treat?

Thanks to its gentle nature, the Cosmelan peel can effectively treat nearly all forms of hyperpigmentation, including melasma that is resistant to laser treatments. Additionally, Dr. Green often employs the Cosmelan peel to address cases where patients have improperly received laser treatments, leading to worsened hyperpigmentation. Some of the primary skin conditions that Dr. Green treats with Cosmelan treatment include:

  • Melasma
  • Post-Inflammatory hyperpigmentation (PIH) from old acne lesions or improper laser treatments
  • Sunspots and age spots
  • Discoloration due to sun damage
  • Dark spots and pigmented blemishes
  • Uneven skin tone
  • Dark marks from acne scars

What is the process like for Cosmelan treatment?

Cosmelan treatment involves a two-step process that includes the application of the Cosmelan 1 mask and a strict home care regimen featuring Cosmelan 2 depigmentation cream, along with other Mesoestetic skincare products. Only expert healthcare professionals, such as board-certified dermatologist Dr. Green, perform this treatment since they are specifically trained in applying the Cosmelan 1 mask. Patients first schedule a consultation with Dr. Green at her private New York City dermatology practice to determine whether the Cosmelan treatment is suitable for their individual skin type, tone, and hyperpigmentation. Dr. Green may conduct a test spot using the Cosmelan peel to ensure there are no adverse allergic reactions to its ingredients in the Cosmelan peel. Once it is confirmed that the individual is a suitable candidate for the Cosmelan peel, the initial application of the Cosmelan mask will be scheduled with Dr. Green.

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Application of the Cosmelan 1 mask

When you arrive at Dr. Green’s private dermatology office on the Upper East Side, your skin will be cleansed with toner provided by the Cosmelan company. Medical photographs will be taken at this time to monitor your treatment progress. Dr. Green will then apply the Cosmelan 1 mask to your entire face. She will instruct you on how long to wear the mask based on the severity of your hyperpigmentation and your skin tone. After the recommended number of hours has passed (4 to 6 hours), wash off the mask at home using a gentle facial cleanser and warm water. You will then receive instructions on how to use the Cosmelan home pack to enhance the results of the treatment. A follow-up appointment with Dr. Green will be scheduled four weeks after the initial application of the Cosmelan 1 mask to evaluate your depigmentation treatment progress and make adjustments to your home care regimen as needed. Dr. Green may perform a second application of the Cosmelan 1 mask to the pigmented areas on your face, depending on your response to treatment.

The Cosmelan home pack and Cosmelan 2 depigmentation cream

The Cosmelan home pack is the second step of the Cosmelan depigmentation process and includes the Melan Recovery moisturizer, Melan 130 Pigment Control sunscreen, and Cosmelan 2 depigmentation serum. After removing the mask, patients should gently cleanse their face and then apply the provided moisturizer to their entire face. For the next seven days, patients should use only a gentle cleanser, the Melan Recovery moisturizer, and the Melan 130 Pigment Control sunscreen on their faces. After a week has passed, you can begin using the Cosmelan 2 cream at home as directed.

The Cosmelan 2 cream is a depigmenting cream that contains a blend of proven active ingredients to enhance the effects of the Cosmelan 1 Mask and help regulate melanin production. Apply a small, pea-sized amount of Cosmelan 2 only to the areas affected by hyperpigmentation and melasma. Use cosmelan 2 at night after cleansing, leaving it on the skin for 15 minutes to ensure full penetration. Afterward, apply the Melan Recovery to the face. The use of Cosmelan 2 cream can be increased to twice a day as long as no irritation, including redness, peeling, stinging, swelling, or tenderness, occurs. Discontinue the Cosmelan 2 cream if irritation arises, as using Cosmelan 2 on irritated skin may exacerbate hyperpigmentation, making it appear more pronounced and prolonging the treatment process. Patients can safely resume using Cosmelan 2 once any skin irritation has resolved. Those sensitive to Cosmelan 2 should inform Dr. Green of any adverse reactions, as she may provide guidance on using it less frequently or switching to a different skin-lightening agent.

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How to maintain the benefits of the Cosmelan treatment

To achieve and maintain optimal cosmetic results, patients must practice proper sun protection and limit sun exposure both during and after treatment. Exposure to sunlight in the treatment area can worsen the appearance of hyperpigmentation and dark spots even after the Cosmelan treatment is complete. Patients should wear sun-protective clothing, such as wide-brimmed hats and sunglasses, and apply broad-spectrum sunscreen with an SPF of 50 or higher to their entire face every day. They should also reapply sunscreen every 90 minutes or after engaging in water activities. Dr. Green recommends layering both a chemical and a physical sunscreen for maximum sun protection. Chemical sunscreens are absorbed into the skin and convert harmful UV rays into harmless heat energy. In contrast, physical sunscreens create a protective barrier on the skin’s surface to prevent UV ray penetration. Patients who diligently avoid sun exposure can expect long-term benefits from Cosmelan treatment, resulting in radiant, clear, and beautiful skin.

What skincare protocol should I follow after completing the Cosmelan peel?

The Cosmelan 2 depigmentation treatment is not intended for long-term use. Dr. Green will advise you on the appropriate duration for using the product. Once you discontinue using Cosmelan 2, Dr. Green will create a personalized skincare protocol tailored to help you achieve and maintain your skin rejuvenation results, so you can look and feel like the best version of yourself. Her exclusive skincare line, MGSKINLABs, includes targeted products formulated to reduce hyperpigmentation in patients of all skin types and tones.

Some of the best skincare creams for lightening hyperpigmentation include tranexamic acid, azelaic acid, vitamin C, and kojic acid. The Vita-C Serum from MGSKINLABs has a high concentration of vitamin C that accelerates skin cell renewal, protects against oxidative stress and free radicals, and brightens skin tone. The Skin Brightening Cream from MGSKINLABs contains kojic acid, glycolic acid, lactic acid, and fruit extracts to gently brighten the skin, resulting in a more even tone and complexion. Both the Vita-C Serum and Skin Brightening Cream can be used twice daily, as they do not contain any known skin irritants and do not increase skin photosensitivity.

Dr. Green may recommend using a retinol or retinoid, which are vitamin A derivatives that help exfoliate the skin, increase skin cell turnover, and stimulate collagen production. Retinols and retinoids are excellent for diminishing hyperpigmentation, softening fine lines and wrinkles, and minimizing the appearance of acne scars and uneven skin texture, resulting in a smooth, clear complexion. The Essential Antioxidant Infusion from MGSKINLABs contains retinol, along with essential vitamins and nutrients to enhance skin tone and texture for comprehensive facial rejuvenation. Retinoids, such as Retin-A or tretinoin, can be obtained through a prescription from a board-certified dermatologist like Dr. Green. When using these vitamin A derivatives, it’s essential to practice sun protection since these ingredients can make the skin more sensitive to the sun.

The most crucial part of any skincare regimen is using a broad-spectrum sunscreen with a minimum SPF of 50. Patients can continue to use the Melan 130 Pigment Control sunscreen after treatment concludes. For maximum protection, patients should apply two types of sunscreen—physical and chemical—to their skin and reapply every 90 minutes. MGSKINLAB’s Hydrating SPF 50 is a physical sunscreen that utilizes zinc oxide to shield the skin from harmful UV rays, along with lactic acid and hyaluronic acid to soften and hydrate the skin.

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Cosmelan – 10 weeks before and after

Frequently Asked Questions (FAQs) about the Cosmelan Peel

Who is the Mesoestetic company?

The Mesoestetic company is a global leader in depigmentation treatments. Mesoestetic has revolutionized the approach to treating melasma and other forms of skin discoloration by introducing several innovative options for pigment control, including the Cosmelan peel, which is suitable for patients of all skin tones, particularly those with darker complexions, such as individuals of AsianHispanic, Mediterranean and African American descent.

Mesoestetic also offers Mesopeel and Dermamelan Intimate, two non-invasive cosmetic treatments designed to eliminate hyperpigmentation. Mesopeel is a gentle, specially formulated chemical peel created to treat hyperpigmentation on the face, around the eyes, in the underarms, inner thighs, and groin. Dermamelan Intimate is a cosmetic treatment that reduces hyperpigmentation in intimate areas, including the buttocks, groin, as well as the vaginal and anal regions. These depigmentation treatments are safe and effective options for patients of all skin tones and types. If you experience hyperpigmentation in other areas of your body, Dr. Green can assess whether Mesopeel or Dermamelan Intimate is a suitable option for you.

What is the Cosmelan depigmentation treatment?

The Cosmelan Peel is an intensive depigmentation treatment that provides both short-term and long-term skin-lightening results. Its active ingredients work to eliminate excess melanin and inhibit the enzyme tyrosinase, which plays a crucial role in melanin production. The treatment begins with the application of the Cosmelan 1 mask, followed by a comprehensive skincare routine that includes the Cosmelan 2 depigmentation cream and other home care products. The Cosmelan treatment is highly effective for all skin types and tones, thanks to its proven active ingredients. It is essential to understand that the Cosmelan treatment is designed to correct hyperpigmentation and promote an even skin tone; it does not serve as a method for lightening one’s natural skin tone.

What type of chemical peel is Cosmelan MD?

Chemical peels are categorized as light/superficial, medium, and deep based on their depth of skin penetration and required downtime. Cosmelan is a medical-grade, medium-depth chemical peel specifically designed to treat hyperpigmentation and melasma. As a medium-depth peel, the Cosmelan treatment may lead to mild side effects, including peeling, redness, or dryness, with minimal downtime.

Does Cosmelan make you peel?

One possible side effect of the Cosmelan 1 mask and Cosmelan 2 cream is peeling in the treatment area. The Cosmelan treatment is designed to accelerate skin cell turnover, and mild peeling, dryness, redness, or irritation may occur during this process. The skincare products that Dr. Green recommends for at-home use after the Cosmelan 1 mask—including topical serums and moisturizers—are intended to maintain adequate hydration and protection for the skin throughout the treatment. Mesoestetic specifically designed the Melan Recovery and Hydra-Vital Factor K moisturizers to be ultra-nourishing during the Cosmelan treatment. If any of these side effects persist or cause discomfort, discontinue the use of the Cosmelan 2 cream until they resolve. Using Cosmelan 2 while experiencing peeling and irritation is counterproductive and may worsen the appearance of hyperpigmentation. During your Cosmelan depigmentation treatment with Dr. Green at her private dermatology office in Manhattan’s Upper East Side, she will provide appropriate aftercare guidelines and schedule a follow-up appointment to assess your progress.

What is the difference between Cosmelan 1 and 2?

The primary difference between Cosmelan 1 and Cosmelan 2 lies in their nature as skincare treatments. Cosmelan 1 is a medical-grade mask that must be applied by a healthcare professional in a clinical setting, such as a board-certified dermatologist’s office like Dr. Michele Green’s in New York City. The Cosmelan 1 mask should be worn for a specific duration, determined by Dr. Green based on your skin tone, the severity of your hyperpigmentation or melasma, and your skin type. After the designated time has passed, the patient should remove the Cosmelan 1 mask using a gentle facial cleanser. In contrast, Cosmelan 2 is a depigmenting skincare cream designed for at-home use by patients, intended to enhance the effects of the Cosmelan 1 mask. Unlike the Cosmelan 1 mask, the Cosmelan 2 cream does not need to be washed off after application. Instead, a small amount should be applied to the areas of hyperpigmentation and allowed to penetrate the skin. Cosmelan 2 can be used once or twice a day, depending on the patient’s tolerance to the cream.

Does Cosmelan have hydroquinone in it?

No, the current formulation of Cosmelan does not contain hydroquinone. The Cosmelan peel includes active ingredients, such as various tyrosinase inhibitors that reduce melanin production in the skin. The primary tyrosinase inhibitors and lightening agents are kojic acid, phytic acid, ascorbic acid (vitamin C), retinol, salicylic acid, niacinamide, and melaphenone (a proprietary tyrosinase inhibitor molecule).

How long should I leave the Cosmelan peel on?

The duration for which the Cosmelan 1 mask should remain on depends on your skin type, tone, and the severity of hyperpigmentation. Some patients may wear the mask for two hours, while others may leave it on for as long as eight hours. Dr. Green, an expert in hyperpigmentation and the Cosmelan peel, will evaluate the optimal duration of the mask to achieve the best cosmetic results.

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How long does Cosmelan last?

Cosmelan treatment can provide incredibly long-lasting rejuvenation results, often requiring just one application of the Cosmelan 1 Mask for many patients. Following the Cosmelan 1 Mask, the second phase of the Cosmelan treatment is the home care regimen. Once the ideal results are achieved from the initial Cosmelan peel, they must be maintained with an appropriate skincare regimen, which includes adequate sun protection and targeted skincare products designed to prevent sun damage. With strict adherence to the aftercare protocol advised by Dr. Green, the results from your Cosmelan depigmentation treatment may be permanent. Limiting sun exposure to the treated area and properly following the at-home maintenance protocol will help you preserve a clear, healthy, radiant, and even-toned complexion.

How much does a Cosmelan treatment cost?

The total cost of Cosmelan treatment varies depending on the geographic location of the office where you receive treatment, your provider’s level of experience, and the number of follow-up treatments needed. The Cosmelan depigmentation treatment is a multi-phase process that includes both an in-office procedure and a home care skincare routine. The first step consists of applying the Cosmelan 1 mask, which Dr. Michele Green performs in her private dermatology office. There is also a range of depigmenting and anti-aging skincare products advised for use at home. Dr. Green customizes the home care protocol based on the patient’s specific needs and personal aesthetic goals. Additional charges may apply for patients who require extra follow-up treatments or repeat applications of the Cosmelan 1 mask due to recurring melasma or hyperpigmentation. While it may be more cost-effective, it is essential to receive treatment from a board-certified dermatologist, such as Dr. Green, to minimize the risk of adverse side effects. During your initial rejuvenation consultation with Dr. Green, the areas of concern will be identified, and an estimate of the total cost of your Cosmelan treatment will be provided.

Where to buy Cosmelan 1 and 2 creams

Many patients wonder where to purchase the Cosmelan peel for treating their hyperpigmentation at home. The Cosmelan 1 mask is not available for over-the-counter purchase, as it must be applied by a healthcare professional, such as a board-certified dermatologist. The Cosmelan 2 cream can only be acquired through a healthcare professional. When undergoing the Cosmelan treatment with Dr. Green, she will provide you with the Cosmelan 2 cream, the Cosmelan homecare kit, and any other essential skincare products to assist you in treating and managing your hyperpigmentation.

Can I use Cosmelan forever?

No, the Cosmelan peel is not meant for permanent use. The Cosmelan peel is formulated to correct and regulate melanin production in the skin. After applying the Cosmelan 1 mask, you should use the Cosmelan 2 cream along with the Cosmelan homecare kit for several months to enhance treatment results. The Cosmelan peel is not intended for long-term use or during the summer, as Cosmelan 2 is photosensitizing. Upon completing the Cosmelan treatment, Dr. Green will provide you with a customized skincare protocol designed to protect your skin from harmful UV exposure, prevent the recurrence of hyperpigmentation, and help you achieve a bright, healthy complexion that lasts.

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45-54 year old male, Cosmelan – 2 months before and after

Is the Cosmelan peel safe?

Absolutely! The Cosmelan peel is a medical-grade treatment designed for safe and effective use on patients of all skin types and tones, including those with darker skin tones. When you receive your Cosmelan peel from board-certified dermatologist Dr. Green in New York City, she will gather a comprehensive medical and family history, review any prior cosmetic procedures you may have undergone, and physically assess the area to determine if you are a suitable candidate for Cosmelan treatment. If you have a history of allergic reactions to topical skincare products, Dr. Green may conduct a patch test to ensure that you don’t develop skin irritation from the products. Dr. Green is an internationally recognized board-certified dermatologist with over two and a half decades of experience providing some of the world’s most discerning individuals with the finest non-invasive treatment options. She will collaborate with you to create a safe and effective rejuvenation plan that leaves you looking and feeling like the best version of yourself.

Is the Cosmelan peel permanent?

The rejuvenating effects of Cosmelan can be long-lasting or even permanent, provided proper maintenance and sun avoidance are followed. Melanocytes, the skin cells that produce melanin, are activated by UV exposure. Therefore, limiting sun exposure and using appropriate sun protection after your Cosmelan peel is essential. Hyperpigmentation and melasma may recur post-treatment if the treated area is exposed to sunlight. Patients should consistently practice proper sun protection during and after treatment by using a broad-spectrum sunscreen with an SPF of 50 or higher and wearing sun-protective clothing such as a wide-brimmed hat and sunglasses.

Is the cosmelan peel worth it?

Yes! The Cosmelan peel is one of the most effective treatments for hyperpigmentation and melasma. This depigmentation procedure can reduce unwanted hyperpigmentation by up to 95% with just one application of the mask. The Cosmelan peel effectively addresses various types of hyperpigmentation, including melasma, sun spots, dark spots resulting from previous acne, and post-inflammatory hyperpigmentation caused by improper laser treatments. Unlike other hyperpigmentation treatments, the Cosmelan peel is safe and effective for patients of all skin types and tones. With few potential side effects, minimal downtime, and consistently stunning cosmetic results that last, most patients agree that the Cosmelan depigmentation treatment is well worth it. When you undergo the Cosmelan depigmentation treatment with Dr. Green at her private dermatology office in Manhattan’s Upper East Side, you can trust that you will achieve a healthy, radiant, and more even skin tone.

How to get started with the Cosmelan peel today

The Cosmelan Peel is the leading depigmentation treatment worldwide, effectively reducing hyperpigmentation and regulating melanin production for long-term skin rejuvenation. Whether Cosmelan is used to address melasma, post-inflammatory hyperpigmentation, sun damage, or other forms of hyperpigmentation, this medical-grade, multi-phase treatment is safe for all skin types, promoting a healthy, radiant, and even skin tone. With minimal potential side effects and downtime, along with consistently impressive cosmetic results, the Cosmelan treatment ranks among the most sought-after cosmetic procedures at Dr. Green’s private dermatology office in Manhattan’s Upper East Side. If you are ready to enhance the appearance of your facial hyperpigmentation or melasma, Dr. Green is here to assist you.

Dr. Michele Green is an internationally recognized, board-certified dermatologist with over two and a half decades of experience providing non-invasive cosmetic treatments to some of the world’s most discerning individuals, including the Cosmelan peel, Mesopeel, and Microneedling. She is frequently voted one of the best dermatologists in New York City by Castle Connolly, Super Doctors, The New York Times, and New York Magazine, celebrated for her commitment to her patients and expertise. Dr. Green adopts a holistic approach and a less-is-more philosophy for facial rejuvenation, customizing each treatment plan to address individual concerns and aesthetic goals. During your consultation with Dr. Green, she will collaborate closely with you to develop a personalized rejuvenation plan that helps you attain and sustain a healthy, radiant complexion and even skin tone. If you’re ready to begin your customized treatment plan today, schedule a consultation with Dr. Green by contacting us online or calling the NYC office at 212-535-3088.

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