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When it comes to the appearance of aging on the skin, facial lines and wrinkles are often the first sign that we encounter. Whether it’s worry lines that begin to deepen, or crow’s feet that appear when we smile, dynamic wrinkles can make us look older than we truly feel. One of the most popular treatments for patients seeking to reduce these fine lines and wrinkles is an injectable cosmetic one, by way of the botulinum toxin. There are currently four forms of this neurotoxin now on the market – Dysport, Botox®, Xeomin, and Jeuveau® . These neuromodulators have increased in popularity each year due to their safety, simplicity of injection, and high patient satisfaction.

Since its initial FDA-approval in 2009, Dysport has become a highly effective treatment option for frown lines and crow’s feet, as it offers safe, quick, and effective treatment with no downtime or side effects. Dysport elegantly smooths and treats fine lines and wrinkles. Dysport is one of the most popular treatments in NYC simply because it offers immediate, high-quality facial rejuvenation in as little as one treatment session. Dysport has a similar formulation to Botox and Jeuveau, and each has unique benefits in terms of developing a treatment plan for facial rejuvenation

If you’re frustrated by the appearance of facial lines and dynamic wrinkles, board-certified cosmetic dermatologist, Dr. Michele Green, is here to help. Dr. Green is a highly experienced cosmetic dermatologist with particular expertise in cosmetic injectables, including neuromodulators and dermal fillers. With over two decades of experience in neurotoxin injections, Dr. Green uses her “less is more” philosophy to create an artful, natural look, reducing the appearance of facial lines and wrinkles. Dr. Green is thrilled to provide Dysport to her patients in her discreet, private, NYC office.

What are Dysport Injections?

Dysport is an FDA-approved, fast-acting, long lasting prescription injection, proven to treat moderate to severe frown lines between your eyebrows, (the glabellar lines), forehead wrinkles, and crow’s feet (lines around the eyes). Dysport is a liquid injectable that relies on a neurotoxin, botulinum toxin type A, to essentially “freeze” the nerve signals to overactive muscles in the face. This reduction in muscle activity then reduces the appearance of dynamic wrinkles on the face, helping to smooth the surface of the skin.

Dynamic wrinkles are formed when the muscles in the face repeatedly contract, and common facial expressions are made. Over time, the repetitive motion of the underlying muscle movement causes lines and wrinkles to form on the skin. It is necessary to stop these muscle contractions, through Dysport treatment, to effectively reduce these dynamic wrinkles in the forehead, eyes, and other areas of the face.

Dysport injections specifically rely on an active ingredient derived from botulinum toxin, abobotulinumtoxinA, which is the same toxin that causes botulism. This botulinum toxin type A formulation is not only safe to use, but is able to essentially “freeze” signals that activate muscle groups. Through this process, targeted muscle groups are forced to relax, reducing the appearance of fine lines and wrinkles within the treatment area. Dysport injections are a non-invasive option for wrinkles, meaning that they require no downtime, and patients can resume normal activity immediately post-treatment. After several Dysport injections, your dynamic lines will continue to be reduced and your wrinkles smooth and skin rejuvenated.

Are Cosmetic Injectables a Long Term Treatment for Facial Rejuvenation?

Cosmetic injectables like Dysport an innovative method to revitalize the appearance of the skin without the need for downtime or invasive surgical procedures. Though the majority of cosmetic injectable treatments are temporary, the results of dermal fillers and other injectables have become increasingly long-lasting over the last decade. Neuromodulators in particular are an excellent long-term solution to facial rejuvenation because, though each treatment session has lasting effects for 3-6 months, continued use of injectables like Dysport and Botox can help to further reduce the appearance of fine lines and wrinkles, helping to turn back the clock on the signs of aging. Additionally, neuromodulators can actually prevent the formation of new facial lines and dynamic wrinkles, helping to preserve youthful looking skin for years to come.

Who makes Dysport Injectable Treatment?

Galderma is the pharmaceutical giant behind Dysport injectable treatment. In 2019, Galderma Laboratories celebrated 10 full years of FDA-approved Dysport treatments in the United States, during which time the neuromodulator has continued to gain wide popularity for the reduction of facial lines. Dysport injections are safely approved for use in 72 different countries, and has over 25 year of successful clinical trials that have proven it to be safe for both therapeutic and aesthetic use. Galderma is a popular innovator in cosmetic dermatology, with products that include Restylane® , Sculptra® , Cetaphil®  brand skincare, and Differin acne gel, among others. Galderma also has a commitment to sustainable consumption and ethical practices to help preserve resources for future generations.

What is the chemistry behind Dysport that makes it work?

Dysport is composed of botulinum toxin, specifically abobotulinumtoxinA. Dysport is an injectable that relaxes your wrinkles by blocking the neural signals that allow a particular muscle to contract. Galderma is responsible for manufacturing Dysport which is the main competitor to Botox which is produced by Allergan. Due to Dysport’s ability to stop these muscle contractions, tone and texture are improved, and superficial and deep wrinkles smoothed and virtually eliminated.

MM restylane dysport 1month angleR MGwatermark

Before and after: Restylane and Dysport – 1 month

Which areas of the face and body does Dysport Treat?

Dysport is able to treat a wide array of facial muscles and wrinkles, including:

  • Glabella lines (worry lines)
  • Forehead lines (frown lines)
  • Crow’s feet (lines around the eyes)
  • Bunny lines (lines from squinting on the nose)
  • Brow lift
  • Correct Brow asymmetry
  • Upper lip lines (smoker’s lines)
  • Gummy smile
  • Jawline contouring for facial slimming; Mandible hypertrophy
  • Hyperhidrosis
  • TMJ
  • Neck cords or bands
  • Wrinkles or dimpling of the chin area
  • Down-turned corners of the mouth (DAO muscle)

TMJ or temporomandibular joint and Dysport

Dysport can also be used to treat TMJ for muscle hypertrophy. TMJ disorder is a common issue that leads to pain along the hinging joint of the jawline. This pain is often caused by an overactive masseter muscle that can reduce motion along the jawline and prevent movement along the jaw. Recent study has shown that neuromodulators are highly effective in the treatment of TMJ disorder. By halting signals to the muscles along the jawline, these overactive muscles can gradually be weakened, thus relieving the pain of TMJ.

Dysport and Hyperhidrosis for underarm sweating

Additionally, Dysport can be used to treat excessive underarm sweating (hyperhidrosis). Dysport can be applied to sweat glands, such as in the underarms, to wondrous effect. Dysport injections can actually target the nervous system, blocking the nerves that activate sweat glands. When these nerves are paralyzed, it can prevent the nerves from activating an overactive sweat gland response, helping to reduce excessive sweating.

How long does it take for Dysport to work?

Some patients wonder how long it takes for Dysport to kick in, and the answer for most patients is “right away!” Typically, patients will see their positive results from Dysport within four days, a couple of days after any initial swelling near the injection site subsides. For some patients, it may take up to two weeks for the full results to become apparent. However, in general, it will only take a few days for optimal results to appear. For some patients, multiple sessions of Dysport injections will be needed in order to ensure optimal results. This is particularly common for treatment areas where stronger muscles are the focus, as well as for male patients who tend to have slightly larger muscle mass. In order to relax these larger muscle groups, multiple treatment sessions spaced at least a month apart can be highly effective.

How long do the effects of Dysport last?

The effects of Dysport can last from 3 to 6 months, depending on the location and the age of the patient injected. Typically, patients will opt for either quarterly or semi-annual treatment sessions in order to continue their successful results from Dysport injections. Also, studies have shown that repeated injections of Dysport will continue to weaken the muscle and may prolong the longevity of injection. Both male patients and younger patients may require more units of Dysport injected in a given area to smooth facial lines and wrinkles, depending on the size of the muscles being treated.

How to make Dysport last longer

Most patients are thrilled with their results after an initial Dysport treatment, as the benefits of Dysport can last up to a full six months for many patients. However, one of the best ways to extend the success of Dysport is to continue with regular “touch-up” appointments. By continuing to engage in Dysport treatment sessions, patients can maximize the effectiveness of the neuromodulator and, in some cases, can permanently reduce the severity of facial lines and dynamic wrinkles.

What is the difference between Dysport vs Botox?

A complete literature review was recently completed, by Dr. Jeffrey Dover n 2018, which confirmed that there were no clinical differences observed between these products.  The main difference in results depends on the dose of the product injected, since diffusion and spread are entirely dose dependent.

Each of these neurotoxins are comparable and effective. However, the units of Dysport cannot be compared with the number of units of Botox or Xeomin, and are not interchangeable. The original Botox formulation, before 1998, had 25ng protein per 100 units. When Botox was reformulated it was reduced to 5 ng protein per 100 units. Dysport has a mean protein content of 4.25 ng per 500-unit vial. Xeomin has the least protein load with 0.44 ng per 100-unit vial.  It is still unclear if this difference in protein load has any clinical significant in the cosmetic indications of Botox. Both Botox and Dysport have the same recovery time, with no downtime. Additionally, they both have the the same effects on facial wrinkles in that they both reduce the appearance of dynamic wrinkles on the face and have results that last for the same period of time.

Is Dysport better than Botox?

Botox currently has FDA approval for glabella, forehead, crow’s feet, among other indications. Botox is also currently approved for migraines, depression, overactive bladder, and temporomandibular joint diseases.  Dysport is currently only approved cosmetically for the glabella area, whereas Botox is approved for multiple treatment areas. Botox uses 20 units to treat the glabella area and Dysport typically used 50 units in the same area. Since the units are not comparable, a direct conversion cannot be inferred.  Both Botox and Dysport have the same safety profile, similar proteins, and side effects. Both Dysport and Botox are considered safe and effective for the temporary treatment of moderate to severe wrinkles.  Both Botox and Dysport seem to last the same amount of time after injection, although the onset of action of Dysport is a few days earlier than Botox. Both the effects of Dysport and Botox are temporary in treating wrinkles and re-injection is needed once the effects wear off.  For patients who find that skincare alone is not treating existing fine lines and wrinkles, both Botox and Dysport are effective ways to treat these facial wrinkles.

32 year old female, 3 weeks after 50 units in forehead and around eyes.

What is the difference between Dysport vs. Xeomin?

Similar to both Dysport and Botox, Xeomin is a neuromodulator that uses botulinum toxin to relax the muscles that cause dynamic wrinkles. Xeomin is a cutting-edge variation on neuromodulators created by Merz Pharmaceuticals. Xeomin differs from Dysport and Botox in that is contains no additives or accessory proteins in its formulation, which can be an excellent option for patients who have developed antibody resistance to products similar to Botox. Antibody resistance is a frustrating issue that certain patients can develop with continued use of Botox over time, which is why Xeomin’s “naked” formulation is considered an exciting development in the world of neuromodulators.

What is the difference between Dysport vs. Jeuveau?

Jeuveau (also referred to as Newtox) is yet another botulinum toxin injectable neuromodulator that helps to reduce the appearance of fine lines. It is the first alternative form of Botox in nearly ten years, since Dysport and Xeomin were put on the market. Jeuveau also uses botulinum toxin to block chemical signals from nerves to muscles in the treatment area, thus reducing the appearance of wrinkles. Just like Dysport, Jeuveau tends to be most effective for 3-6 months after treatment. Jeuveau tends to show full results after about two weeks, and side effects are minimal.

The primary difference between Jeuveau and Dysport is that Jeuveau relies on an innovation known as Hi-Pure. Within the manufacturing process of Jeuveau, an additional purification process of the protein takes place, which is thought to make the formulation safer. Additionally, unlike Dysport and Botox, Jeuveau is exclusively used for cosmetic purposes, rather than treating medical issues such as hyperhidrosis, TMJ disorder, or muscle spasms.

What is the best neuromodulator to use?

When it comes to which neuromodulator to use for treatment, there is no one “best” option. Each formulation has its own exceptional benefits, and should be chosen based on the particular needs of the patient. For example, patients who are interested in using neuromodulators for the first time for cosmetic use may opt for Dysport. Patients seeking treatment for chronic migraines may opt to use Botox. Patients who have experienced antibody resistance to Dysport or Botox may be interested in using Xeomin to continue to see improvements from neuromodulator injections. When you work with Dr. Green, she will work with you to discuss which neuromodulator is best for you, carefully considering your medical history, as well as your individual needs and aesthetic goals.

xeomin 1724577325

Who is best qualified to inject Dysport?

One of the main concerns is the qualifications of the injector to treat you with injectables such as Botox, Dysport, and Juvederm® .  Both plastic surgeons and dermatologists are trained to do these procedures. It is very important not to trust “bargains” or “groupons” for your cosmetic injections. It is always best to consult a board certified dermatologist who has years of experience with cosmetic injectables such as Dysport and Juvederm to have the best results and avoid complications. The best injector will be someone qualified with years of experience in treating facial wrinkles.

Who is the best candidate for Dysport Treatment?

The best candidate for Dysport injections is a patient 18 years of age or older who is healthy with no previous adverse reactions to botulinum products.  If you have any neurologic medical conditions, such as ALS or myasthenia gravis, these could be contraindications to Dysport injections, so it is best to consult your treating physician before any injections. Also, any patient with a known allergy to albumin or cow’s milk protein should not have Dysport injected.  If you are allergic to Botox of Myobloc then you are not a candidate for Dysport injections.

What are the side effects of Dysport injections?

In general, side effects from Dysport injections are very mild. Common side effects of Dysport include:

  • bruising
  • localized swelling at the site of injection
  • droopy eyelids, swelling of the eyelids

Occasionally, Dysport injections can lead to serious side effects. These serious side effects include:

  • allergic reaction
  • upper respiratory tract infection
  • sinus infection and sore throat
  • loss of bladder control or muscle weakness

There is a warning of the possibility of distant spread of toxin after Dysport injection. Symptoms of toxin spread, if this occurs, will develop weeks to months after injection, and may include blurred vision, severe muscle weakness (almost as if the patient had taken a muscle relaxant), or difficulty  talking. Additionally, swallowing and breathing difficulties are extremely rare, but have been reported, mostly in children with underlying neurologic issues.

IMAGE11 35 44 year old woman treated with dysport MGWatermark

35-44 year old woman treated with Dysport in Glabella area

What are the other uses of Dysport besides cosmetic use?

Dysport has the similar formulation and function as Botox, which means that it can also be successfully used in medical treatments. These treatments include cervical dystonia, an involuntary neck muscle contraction, upper limb spasticity, and lower limb spasticity in pediatric patients. Additionally, treatment for TMJ disorder and hyperhidrosis are considered to be medical uses for neuromodulators.

Is Dysport Safe?

Dysport, when provided by a board-certified healthcare professional, is very safe and is associated with generally mild side affects, such as injection site pain or swelling in the treatment area. However, when Dysport is administered by an inexperienced injector, severe, life-threatening side affects are more likely to occur. For this reason, it is vital that you work with an experienced, board-certified medical doctor. Medical spas, aesthetics centers, and “botox parties” often offer Dysport injections, but in order to ensure both safe and satisfactory results, a board-certified dermatologist is the best option. Dr. Green is an artful injector of neuromodulators, dermal fillers, and other injectable cosmetic treatments, and she has over two decades of experience helping patients look and feel like the best versions of themselves.

When considering Dysport or any injectable treatment, it’s best to examine the medication guide, which contains important safety information and can help to determine any potential contraindications. Do not use Dysport if you are allergic to any of its ingredients or are allergic to cow’s milk protein, or have a skin infection at the site of injection, are pregnant or breastfeeding. If you have any underlying neurologic disorders, swallowing or breathing problems, please consult with your primary physician to see if you are permitted to have Dysport injections. If you have any allergies to any botulinum toxin product, this is a contraindication to Dysport injections.

How does the procedure of Dysport work?

You can schedule a consultation with Dr. Green for Dysport in her private Upper East Side NYC office.  Dr. Green will examine your facial structure and study your facial muscles, when squinting and frowning, so she can determine where to best place the injections for maximum impact. Photos will be taken in all angles to help document your treatment plan. Prior to your first Dysport procedure, we will apply a topical numbing cream to lessen any discomfort at the injection site.

Next, she’ll carefully inject small amounts of Dysport® into the treatment area to prevent them from wrinkling, smoothing existing frown lines and wrinkles, and preventing new lines from forming. There is minimal discomfort during treatment. We advise patients to refrain from blood thinners before cosmetic injections to avoid any bruising or downtime. There is some evidence which shows that continued muscle contractions after injection prolongs the effect of your Dysport injections, so we suggest that you continue to wrinkle the treated area for several hours after injection. Men may require more units of Dysport than women because they generally have stronger muscles. Dysport results generally take four days to be evident. Our patients are able to return to work and continue their normal daily activities immediately following their treatment, a huge advantage of non-invasive injectable treatments over surgical procedures.

How much Dysport do I need?

The answer to how much Dysport a patient needs varies widely depending on the severity of wrinkles, the size of the treatment area, as well as the specific treatment plan. Typically, when it comes to more subtle facial lines like crow’s feet, around 25 units of Dysport are used for each treatment site. For larger areas, as well as for treatment of stronger facial muscles such as the muscles around the jawline, a higher amount of units will be needed to optimize results.

It’s good to note that Dysport does not have the same concentration of botulinum toxin type A per unit as Botox. This means that, when it comes to Dysport injections, a larger amount of units are typically needed than Botox. Most doctors use the ratio of 2.5: 1 for Dysport to Botox, which means that 25 units of Dysport are near the equivalent of 10 units of Botox, but there is no exact ratio between the two. With all injectable treatments, including Botox and Dysport, Dr. Green uses a “less-is-more” approach, ensuring that patients see results without negatively affecting the muscle.

How many units of Dysport are needed for forehead wrinkles?

As the primary muscle of the forehead is relatively thin and flat when compared to other facial muscles, forehead wrinkles can be treated with a moderate amount of Dysport. Generally, around 40 units of Dysport are needed, but this varies somewhat from patient to patient. Male patients typically have stronger facial muscles than women, and may require more units of Botox into he injection site to treat the area.

How much is Dysport per unit?

The cost of Dysport varies on the amount of units you need and the areas being treated. Every patient is different and the exact amount of Dysport needed will be determined at your consultation. In general, the cost typically varies based on the expertise of the injector. Dr. Green was on of the first dermatologists in NYC to utilize Botox and Dysport for cosmetic wrinkles, to treat frown lines, glabella lines, and crow’s feet, among other areas. When you work with Dr. Green, she will create a customized injection package designed for your needs.

Male Dysport patient, before and after photo

The results from Dysport® are visible within a few days and the results last for at least 3-4 months. Dr. Green will answer any questions you have about these injections so that you can make the best choice for your individual circumstances.

How do I get started with Dysport Injections today?

Cosmetic injectables, like Dysport and Botox, are the number one, most popular cosmetic procedure in the office of Dr. Michele Green. Dr. Green is known as injecting the “best Botox” in NYC and prides herself in her aesthetic artistry in cosmetic injections. Her “less is more” approach to Botox, Dysport, Juvederm and Restylane, have made her consistently voted as one of the best dermatologists in NYC by Castle Connolly, the New York Times, Super Doctors, and New York Magazine. If you would like to smooth your fine lines and wrinkles, and rejuvenate your appearance, then it’s time to make a consultation with Dr. Green today. Please contact us online today or call 212-535-3088 to learn more about whether Dysport® may be right for you.

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